Cisplatin induced hyponatremia

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August undefined, 2024

WebWe report a rare case of severe hyponatremia due to cisplatin-induced syndrome of inappropriate secretion of antidiuretic hormone (SIADH) in a 74-year-old male with a … WebFeb 1, 2016 · The marked urinary losses of sodium in combination with a negative sodium balance led to the diagnosis of cisplatin-induced renal salt wasting syndrome (RSWS). The subsequent clinical...

Cisplatin-induced acute hyponatremia leading to a seizure and …

WebAug 18, 2024 · Volume expansion and dilutional hyponatremia, without neurologic symptoms, can also be induced when isotonic mannitol is used as a flushing solution during transurethral resection of the prostate or bladder. (See "Hyponatremia following transurethral resection, hysteroscopy, or other procedures involving electrolyte-free … WebCisplatin is a well-known chemotherapeutic agent that can be associated with hyponatremia. Mechanisms of cisplatin-induced hyponatremia include renal salt wasting syndrome … birsrestho motiur rahman

Cancer therapy-induced hyponatremia: A case …

WebDec 16, 2024 · Cisplatin induces acute ischemic injury, resulting in decreased renal medullary blood flow ( 24) and renal tubular cell damage ( 25 ). Meanwhile, cisplatin can block calcium ion channels to reduce COX-2 and prostaglandin, cause vasoconstriction, and eventually lead to aggravation of hypoxia ( 26 ). WebThe mainstay approach to prevent cisplatin-induced nephrotoxicity is administering intravenous (IV) hydration with isotonic saline to increase renal blood flow, and decline in half-life of cisplatin and urinary cisplatin concentration. 5 Additionally, many other agents have been studied, such as mannitol, N-acetylcysteine, and furosemide ... WebFeb 16, 2024 · cycles of therapy (with cumulative cisplatin dose of Cancer therapy-induced hyponatremia: A case-illustrated review Karyne Pelletier, Marko Škrtić and Abhijat … birss partick

Cisplatin-induced hyponatremia in malignancy: comparison …

Carboplatin-induced Renal Salt Wasting Syndrome in

WebCisplatin Induced Hearing Loss Model; Noise Induced Hearing Loss Model; In Vitro Research Model . Cochlea Explant Culture; Ototoxicity Evaluation. ... Hyponatremia (Surgery-induced Hyponatremia Model) Leukopenia (Cyclophosphamide-induced Leukopenia Model) Hepatic and Biliary Disorders. WebHyponatremia after chemotherapy is not an uncommon clinical syndrome. Both renal salt-wasting syndrome (RSWS) and syndrome of inappropriate antidiuretic hormone secretion (SIADH) have been reported as the underlying mechanisms for chemotherapy-induced hyponatremia.However, these two clinical syndromes have distinct clinical … birssan dealers for electrick jeys for 2015WebMay 19, 2024 · Cisplatin treatment may cause hyponatremia through SIADH, related to both higher secretion of and sensitivity to ADH . Nausea and vomiting, which are common side effects of platinum … birsstrasse 134

"WebDec 21, 2024 · Inamori M, Inohara H, Horii A. Diﬀerential diagnosis of hyponatremia induced by cisplatin-con taining chemotherapy: syndrome of inappropriate secretion of an tidiuretic hormone (SIADH) or renal ... " - Cisplatin induced hyponatremia

Cisplatin induced hyponatremia

Renal salt-wasting syndrome in a patient with cisplatin-induced ...

WebThe possibility of Cisplatin induced renal salt wasting was considered. The patient was started on Fludrocortisone 0.1mg twice daily, oral salt tablets 1g QID, sodium bicarbonate tablets 650mg TID and normal saline at 150ml/h. ... PROFOUND HYPONATREMIA AND DEHYDRATION: A CASE OF CISPLATIN INDUCED SALT LOSING NEPHROPATHY. … WebIntroductionLung cancer (LC) is highly prevalent worldwide, with elevated mortality. In this population, taste and smell alterations (TSAs) are frequent but overlooked symptoms. The absence of effective therapeutic strategies and evidence-based

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WebJun 11, 2024 · Concurrent hypoxemia, which may result from noncardiogenic pulmonary edema or hypoventilation, can exacerbate hyponatremia-induced cerebral edema and lead to a vicious cycle ending in death . Impending herniation can be successfully reversed with a 4 to 6 mEq/L increase in the serum sodium concentration . In contrast to the clinical … WebBoth renal salt-wasting syndrome (RSWS) and syndrome of inappropriate antidiuretic hormone secretion (SIADH) have been reported as the underlying mechanisms for chemotherapy-induced hyponatremia. However, these two clinical syndromes have distinct clinical characteristics and managements.

WebJan 13, 2024 · In addition, significant hyponatremia signals were detected for oesophageal, lung, and renal cancers. Conclusions: Hyponatremia has been reported in women and patients with lung cancer... WebElectrolyte disorders with platinum-based chemotherapy: mechanisms, manifestations and management. Platinum chemotherapy, particularly cisplatin, is commonly associated with …

WebApr 6, 2024 · Treatment-related grade 3/4 hyponatremia was reported in 5%–7% of MIBC patients treated with pre-operative ... NAC and prolonged survival. 34-36 It is hypothesized that these mutations may increase the sensitivity of tumor cells to cisplatin-induced DNA damage, thereby enhancing the drug's efficacy in these tumors. 37 The incidence of DDR ... WebHyponatremia (Surgery-induced Hyponatremia Model) Leukopenia (Cyclophosphamide-induced Leukopenia Model) Hepatic and Biliary Disorders. ... Cisplatin Induced Hearing Loss Model ; Noise Induced Hearing Loss Model; In Vitro Research Model . Cochlea Explant Culture ; Ototoxicity Evaluation.

WebAbstract We report a rare case of cisplatin-induced acute hyponatremia leading to a seizure and coma. A 66-year-old woman with breast cancer received adjuvant chemotherapy with docetaxel and cisplatin. She had no nausea, vomiting, or diarrhea during or after chemotherapy administration.

WebNov 1, 1997 · Cisplatin regimens can lead to a more or less pronounced hyponatremia in 4 to 10% of cases due to salt wasting with hypomagnesemia and normokaliemia. … dan hernandez electric lakewayWebwasting due to cisplatin therapy. Although patients with cancer have hyponatremia due to many etiologies (Table 1), SIADH is the most common etiol- ... hyponatremia via potentiation of ADH release or action, in-cluding vinblastine, vincristine, and cyclophosphamide (7). ... or steroid-induced ulcer disease) Decreased effective … birsstrasse 16 baselWebCDDP-induced hyponatremia has also occurred in a case of renal salt-wasting syndrome, 4 in patients with nausea/vomiting/anorexia, and when vigorous hydration was … dan hernandez fishing videosWebHyponatremia after chemotherapy is not an uncommon clinical syndrome. Both renal salt-wasting syndrome (RSWS) and syndrome of inappropriate antidiuretic hormone … dan hernandez attorney el pasoWebMar 1, 2024 · We report a rare case of cisplatin-induced acute hyponatremia leading to a seizure and coma. A 66-year-old woman with breast cancer received adjuvant … dan hernandez fishing rodsWebPhysicians may not always give proper attention in time to undesirable drug-induced hyponatremia. Effective clinical management can be handled through awareness of the adverse effect of certain ... Platinum compounds (cisplatin, carboplatin)42-44 Alkylating agents (intravenous cyclophosphamide,45-47 melphalan,48 ifosfamide49) dan hernandez fishermanWebThe syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is a condition characterized by hypotonic and euvolemic hyponatremia along with urinary hyperosmolarity, resulting from antidiuretic hormone (ADH) release in the absence of adequate stimuli. This term was first used in 1957, when Schwartz et al described … birsstrasse 170 basel