WebPR:000007725 fizzy-related protein (term hierarchy) InterPro Domains. IPR024977 Anaphase-promoting complex subunit 4, WD40 domain. IPR033010 The WD repeat Cdc20/Fizzy family. IPR001680 WD40 repeat. IPR019775 WD40 repeat, conserved site. IPR036322 WD40-repeat-containing domain superfamily. WebSep 15, 2005 · The rap (retina aberrant in pattern) gene encodes the Fizzy-related protein (Fzr), which as an activator of the ubiquitin ligase complex; APC/C (anaphase promoting complex/cyclosome) facilitates the cell cycle stage-specific degradation of cyclins. Loss-of-function mutations in rap cause unscheduled accumulation of cyclin B in the developing …
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WebPredicted to act upstream of or within positive regulation of ubiquitin protein ligase activity. Predicted to be part of anaphase-promoting complex. Orthologous to human FZR1 (fizzy and cell division cycle 20 related 1). [provided by Alliance of Genome Resources, Apr 2024] Other designations. fizzy-related protein homolog WebNov 21, 2008 · Abstract. The Fizzy/Cdc20 family of proteins are essential activators of the anaphase-promoting complex/cyclosome (APC/C), a multisubunit E3 ubiquitin … siemens historical institute berlin
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WebMar 25, 2024 · The tumor suppressor protein p53, also known as ‘the guardian of the genome,’ is appropriately folded by Hsp90. Another cell cycle regulatory protein, Fizzy related homolog (Fzr), is the substrate of Hsp90, which controls the proliferative cycle of Drosophila, yeast, Caenorhabditis elegans even mammals. The inhibition of Fzr leads to … WebApr 10, 2024 · It's delicious, fizzy, and refreshing! A Dirty Dr Pepper is a non-alcoholic drink made with Dr Pepper, coconut syrup, and lime juice. It's delicious, fizzy, and refreshing! ... Related recipes. Try these homemade drink recipes next: Raspberry Lemonade Slushie ... 63 g Protein: 0.03 g Sodium: 61 mg Potassium: 8 mg Fiber: 0.03 g Sugar: 61 g ... WebFeb 21, 2014 · In addition, Hnt represses the expression of another transcription factor, Cut, and this allows fizzy-related protein (Fzr; also known as CDH1 in humans), an activator of the APC/C (anaphase ... the pot belly belconnen